Microchip Platform for Imaging-based Efficacy Testing of Cells & Reagents for Immunotherapy

Time: 1:00 pm
day: Workshop


• A microchip platform for live-cell imaging of thousands of individual cells within larger populations and show how we use it to assess heterogeneity in cytotoxic response and serial killing by NK cells
• A microchip platform for generating tumor spheroids for studies of the tumor microenvironment and how NK attack solid tumors
• Examples of how these platforms have been utilized to get mechanistic understanding of the cytotoxic process during NK serial killing, how NK cells respond to changes in the tumor microenvironment and to test efficacy of drugs for immuno-oncology