Graham Pockley

Graham Pockley

Company: Alphageneron Pharmaceuticals

Job title: Interim Chief Scientific Officer


Following Patient Outcomes with Circulating Cancer Cell Biomarkers to Determine Response & Efficacy 2:00 pm

Understanding the characteristics of therapy in vivo with exosomal membrane protein and circulating tumor cells assay development Leveraging membrane-bound HSP-70 as a marker of tumor burden and therapeutic response Tracking long-term patient response and tumor burden by measuring viable tumor volume Discussing the molecular profiles of responding patientsRead more

day: Day One Track B PM

Mapping Stimulatory Pathways for NK Cells via HSP70 & Characterizing Cell Responses 2:30 pm

Achieving ex vivo activation with HSP70 to activate desirable phenotype of NKs Identifying a clearly defined target, activation pathway, mechanism of action, and levels of specificity Demonstrating clearly characterised phenotypes of NKs activated by HSP70 to obtain a ‘suitable’ product in line with regulatory expectations Applying activation with HSP70 to manufacturing of NKs in autologous…Read more

day: Innate Immune Biology Bootcamp

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