Richard Childs

Richard Childs

Company: NIH

Job title: Rear Admiral, Commissioned Corps Unites States Public Health Service, NHLBI


Genetic Manipulation of Chemotactic Receptors as a Novel Strategy to Modulate the Homing of Adoptively Transferred Ex Vivo Expanded NK Cells 2:30 pm

• Ex vivo expansion of NK cells with feeder cells induces transcriptional shifts in thousands of protein coding genes • Expanded NK cells have significant alterations in chemokine receptors (CRs) including downregulation of CXCR4 and upregulation of CCR5 and other CRs which may lead to preferential NK cell trafficking to the liver rather than the…Read more

day: Workshop

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