Preclinical Characterization of NK Cells Derived from Pluripotent Stem Cells and Peripheral Blood

  • Comparative analysis of NK cells derived from patient-matched induced pluripotent stem cells and peripheral blood to identify intrinsic phenotypic and metabolic differences
  • Functional assessment of cytotoxicity and persistence to understand donor and source-dependent variability in NK cell performance
  • Insights into how preclinical findings can guide optimization of cell sourcing, metabolic conditioning, and next-generation NK therapy design