Clinical-Grade Manufacturing of Hard-to Transduce Cells Using Baboon Envelope Pseudotyped Lentiviral Vector
Time: 9:00 am
day: Day 1 AM
Details:
- Clinical-grade manufacturing of hard-to-transduce cells remains challenging since currently available technologies either lead to low transduction efficiencies or are unsuitable for clinical production
- Baboon envelope pseudotyped lentiviral vectors (BaEVLVV) facilitate the genetic engineering of hard-to-transduce cells such as NK, γδT, B cells and hematopoietic stemcells overcoming the limitations offered by other vector types
- We present here the first BaEV LVV platform for clinical-grade cell and gene therapy manufacturing enabling to overcome production challenges of therapies based on hard-to-transduce cells
