Generation of Allogeneic CAR-NKT Cells from Hematopoietic Stem and Progenitor Cells Using a Clinically Guided Culture Method
Time: 11:30 am
day: Day 1 - Track A - AM
Details:
- Generate HSPC-engineered allogeneic CAR-NKT cells using a clinically guided culture method, with high yield, high purity, and robustness
- These allogeneic CAR-NKT cells:
- Demonstrated potent antitumor efficacy and multiple tumortargeting mechanisms
- Depleted immunosuppressive cells in the tumor microenvironment and antagonized tumor immune evasion
- Exhibited a stable hypoimmunogenic phenotype, and did not induce detectable graft versus host disease or cytokine release syndrome
